Appendix
Sanger IDa |
Gene |
Protein function |
Fraction |
M. tuberculosis Sanger IDb |
Expression by M. tuberculosis |
Identity |
Class 0 – Virulence, Detoxification, Adaptation |
||||||
ML0862 |
ephD |
putative oxidoreductase |
M |
Rv2214c |
Pd |
80.4% |
ML1623c |
htpG |
heat shock protein Hsp90 family |
CW |
Rv2299c |
P |
80.8% |
ML2269 |
bpoC |
possible peroxidase BPOC (non-heme-peroxidase) |
C/CW |
Rv0554 |
– |
83.5% |
ML2490c |
clpB |
heat shock protein |
CW |
Rv0384c |
Pd |
89.0% |
ML2588 |
yrbE1B |
conserved membrane protein |
CW |
Rv0168 |
T |
85.1% |
Class I – Lipid Metabolism |
||||||
ML0134 |
fadD22 |
putative acyl-CoA synthetase |
M |
Rv2948c |
T |
75.9% |
ML0135 |
pks1 |
putative polyketide synthase |
CW |
Rv2946c |
Pd |
90.5% |
ML0138c |
fadD28 |
acyl-CoA synthetase |
M/CW |
Rv2941 |
T |
81.9% |
ML0139 |
mas |
putative mycocerosic synthase |
M/CW |
Rv2940c |
P/Td |
88.0% |
ML0323 |
cysS |
putative cysteinyl-tRNA synthase |
M/CW |
Rv3580c |
– |
86.5% |
ML0389 |
choD |
putative cholesterol oxidase |
CW |
Rv3409c |
T |
88.6% |
ML0452c |
|
probable alpha-mannosyltransferase PimA |
M |
Rv2610c |
– |
82.3% |
ML0726c |
bccA |
acetyl/propionyl CoA carboxylase [alpha] subunit |
M |
Rv3285 |
Pd |
88.7% |
ML0731c |
accD5 |
acetyl/propionyl CoA carboxylase [beta] subunit |
M |
Rv3280 |
Pd |
88.7% |
ML1158 |
atpA4 |
probable acetyl-CoA acetyltransferase |
C |
Rv1323 |
P/T |
86.9% |
ML1191c |
fas |
fatty acid synthase |
M/CW |
Rv2524c |
P/Td |
85.8% |
ML1229 |
pks4 |
type-I polyketide synthase |
CW |
Rv1180 Rv1181 |
– |
81.3% 75.3% |
ML1234c |
fadD21 |
possible acyl-CoA synthase |
CW |
Rv1185 |
T |
72.4% |
ML1657 |
accD6 |
acetyl/propionyl CoA carboxylase [beta] subunit |
CW |
Rv2247 |
T |
92.8% |
ML1806cc |
inhA |
NADH-dependent enoyl-[acyl-carrier-protein] reductase |
C/CW |
Rv1484 |
– |
90.3% |
ML1996 |
nrp |
probable peptide synthase |
CW |
Rv0101 |
Pd |
65.7% |
ML2349 |
papA5 |
possible conserved polyketide synthase associated protein |
CW |
Rv2939 |
T |
83.8% |
ML2353c |
ppsE |
polyketide synthase |
M/CW |
Rv2935 |
P/Td |
82.0% |
ML2355c |
ppsC |
polyketide synthase |
M/CW |
Rv2933 |
P/Td |
82.3% |
ML2358c |
fadD26 |
probable acyl-CoA synthase |
CW |
Rv2930 |
P/Td |
76.8% |
ML2563c |
fadE5 |
acyl-CoA dehydrogenase |
C/M |
Rv0244c |
Pd |
89.4% |
ML2565 |
fabG4 |
possible oxidoreductase |
M/CW |
Rv0242c |
P/Td |
84.8% |
ML2655c |
fbpC2 |
secreted antigen 85C |
C |
Rv0129c |
P |
81.3% |
Class II – Information Pathways |
||||||
ML0492c |
ppiB |
putative peptidyl-prolyl cis-trans isomerase B |
M |
Rv2582 |
– |
72.5% |
ML0548 |
priA |
putative primosomal protein N’ (Replication factor Y) |
CW |
Rv1402 |
Pd |
80.7% |
ML0826 |
glyS |
putative glycyl-tRNA synthase |
M |
Rv2357c |
Pd |
90.2% |
ML0854 |
gpsI |
putative polyribonucleotide phosphorylase / guanosine pentaphosphate synthetase |
M/CW |
Rv2783c |
Pd |
90.0% |
ML0987 |
recA |
recA protein |
C |
Rv2737c |
P/Td |
46.7% |
ML1174 |
rphA |
ribonuclease RPHA tRNA (tRNA nucleotidyl transferase) |
C |
Rv1340 |
– |
88.8% |
ML1381c |
polA |
DNA polymerase I |
M |
Rv1629 |
Pd |
85.2% |
ML1382 |
rpsA |
30S ribosomal protein S1 |
C/M |
Rv1630 |
P/Td |
93.8% |
ML1498c |
typA |
possible GTP-binding, protein elongation factor |
CW |
Rv1165 |
Pd |
85.2% |
ML1553 |
proS |
prolyl tRNA synthetase |
M/CW |
– |
– |
– |
ML1590c |
frr |
ribosome recycling factor |
C |
Rv2882c |
P/T |
90.8% |
ML1598c |
rpsB |
30S ribosomal protein S2 |
M |
Rv2890c |
P/Td |
91.5% |
ML1659c |
rnc |
RNAse III |
CW |
Rv2925c |
– |
86.7% |
ML1702c |
gatA |
probable glutamyl-tRNA amidotransferase |
C |
Rv3011c |
– |
88.5% |
ML1735c |
nrdI |
NrdI-family protein |
C |
Rv3052c |
– |
79.7% |
ML1844c |
rplF |
50S ribosomal protein L6 |
M |
Rv0719 |
Pd |
90.5% |
ML1847c |
rplE |
50S ribosomal protein L5 |
M/CW |
Rv0716 |
P/Td |
91.4% |
ML1848c |
rplX |
50S ribosomal protein L24 |
CW |
Rv0715 |
P/Td |
93.3% |
ML1857c |
rpsC |
30S ribosomal protein S3 |
M |
Rv0707 |
P/Td |
95.0% |
ML1860c |
rplB |
50S ribosomal protein L2 |
M |
Rv0704 |
P/Td |
92.1% |
ML1861c |
rplW |
50S ribosomal protein L23 |
M |
Rv0703 |
P/Td |
85.0% |
ML1890cc |
rpoC |
[beta]’ subunit of RNA polymerase |
C/M/CW |
Rv0668 |
P/Td |
95.6% |
ML1891cc |
rpoB |
[beta] subunit of RNA polymerase |
C/M/CW |
Rv0667 |
T |
94.9% |
ML1906cc |
nusG |
transcription antitermination protein nusG |
C |
Rv0639 |
P |
93.4% |
ML1956c |
rplQ |
50S ribosomal protein L17 |
M |
Rv3456c |
Pd |
89.9% |
ML1959c |
rpsK |
30S ribosomal protein S11 |
CW |
Rv3459c |
T |
81.9% |
ML2393 |
greA |
probable transcriptional elongation factor |
C |
Rv1080c |
Pd |
94.5% |
ML2684c |
ssb |
single strand binding protein |
C |
Rv0054 |
P |
89.3% |
Class III – Cell Wall and Cell Processes |
||||||
ML0042 |
|
putative conserved membrane protein |
CW |
Rv3882c |
Pd |
72.1% |
ML0047c |
|
putative conserved transmembrane protein |
CW |
Rv3877 |
– |
74.0% |
ML0092 |
glf |
putative UDP-galactopyranose mutase |
CW |
Rv3809c |
Pd |
86.6% |
ML0093 |
glfT |
bifunctional UDP-galactofuranosyl transferase |
M |
Rv3808c |
P/Td |
85.4% |
ML0096 |
|
putative conserved transmembrane protein |
M/CW |
Rv3805 |
– |
80.9% |
ML0105c |
embA |
putative arabinosyl transferase |
CW |
Rv3794 |
Pd |
64.2% |
ML0136 |
llpX |
putative conserved lipoprotein |
M/CW |
Rv2945c |
P/T |
76.4% |
ML0203 |
|
putative conserved transmembrane protein |
CW |
Rv3635 |
– |
77.2% |
ML0227 |
|
hypothetical protein |
C |
Rv3605c |
– |
85.4% |
ML0319c |
lpqE |
putative lipoprotein |
CW |
Rv3584 |
P |
63.4% |
ML0488c |
secF |
putative protein-export membrane protein |
M |
Rv2586c |
– |
72.1% |
ML0557c |
lprG |
putative lipoprotein |
M/CW |
Rv1411c |
P/Td |
68.1% |
ML0569c |
|
possible conserved exported protein |
M |
Rv1433 |
– |
68.3% |
ML0595 |
|
probable conserved ATP-binding protein ABC transporter |
C |
Rv1463 |
P |
85.8% |
ML0644c |
|
putative integral membrane protein |
M/CW |
Rv3193c |
P |
86.1% |
ML0691c |
dacB1 |
putative D-alanyl-D-alanine carboxypeptidase |
M |
Rv3330 |
– |
77.2% |
ML0779c |
secA |
putative preprotein translocase subunit |
CW |
Rv3240c |
Pd |
87.5% |
ML0810c |
|
possible secreted protein |
CW |
Rv3212 |
P/Td |
79.9% |
ML0857c |
|
putative conserved transmembrane protein |
CW |
Rv2219 |
– |
80.8% |
ML0910 |
murF |
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase (D-alanine:D-alanine-adding enzyme) |
CW |
Rv2175c |
– |
75.5% |
ML0977c |
ftsK |
cell division transmembrane protein |
CW |
Rv2748c |
Pd |
78.1% |
ML1248 |
|
probable macrolide ABC-transporter protein, ATP binding component |
CW |
Rv2477c |
Pd |
92.3% |
ML1334c |
|
possible conserved membrane protein |
CW |
Rv2091c |
T |
62.9% |
ML1425c |
|
probable sugar ABC-transport integral membrane protein |
M |
Rv2039c |
– |
79.2% |
ML1562c |
efpA |
putative transmembrane efflux protein |
CW |
Rv2846c |
T |
86.5% |
ML1622 |
ffh |
signal recognition particle protein |
M |
Rv2916c |
Pd |
87.8% |
ML1633cc |
|
probable exported protease |
M |
Rv2224c |
P/Td |
84.8% |
ML1667c |
|
possible conserved membrane or secreted protein |
M |
Rv2969c |
P |
65.5% |
ML1769 |
uspB |
probable sugar ABC transporter integral membrane protein |
C |
Rv2317 |
– |
85.0% |
ML1808c |
|
possible conserved membrane protein |
M |
Rv1481 |
P |
91.0% |
ML1839c |
sppA |
protease IV, signal peptide peptidase |
M |
Rv0724 |
P |
80.2% |
ML2095c |
psts3 |
periplasmic phosphate-binding lipoprotein |
M |
Rv0928 |
P |
77.3% |
ML2296 |
|
putative conserved transmembrane protein |
M |
Rv3669 |
– |
77.9% |
ML2305 |
|
probable anion transporter ATPase |
M |
Rv3679 |
T |
84.2% |
ML2378 |
mmpL4 |
conserved large transmembrane protein |
CW |
Rv0450c |
T |
78.4% |
ML2410c |
|
conserved transmembrane protein. |
CW |
Rv0528 |
– |
80.9% |
ML2433 |
|
conserved membrane protein |
M |
Rv0497 |
– |
54.2% |
ML2454c |
hbhA |
possible hemagglutinin |
C/M/CW |
Rv0475 |
P/Td |
81.4% |
ML2687c |
|
conserved transmembrane protein |
CW |
Rv0051 |
– |
78.7% |
Classe VII – Intermediary Metabolism and Respiration |
||||||
ML0065 |
ethA |
putative monooxygenase |
CW |
Rv3854 |
P/Td |
80.1% |
ML0074 |
glpQ1 |
putative glycerophosphoryl diester phosphodiesterase |
CW |
Rv3842c |
T |
88.8% |
ML0108c |
|
putative oxidoreductase |
M |
Rv3791 |
– |
89.0% |
ML0109c |
|
putative FAD-linked oxidoreductase |
CW |
Rv3790 |
Pd |
86.6% |
ML0127c |
|
possible methyltransferase |
M/CW |
Rv2959c |
– |
76.1% |
ML0150c |
pgi |
glucose-6-phosphate isomerase |
CW |
Rv0946c |
– |
85.5% |
ML0155 |
sucC |
succinyl-CoA synthase [beta] |
CW |
Rv0951 |
Pd |
86.7% |
ML0161 |
purH |
putative phosphoribosylamino-imidazolecarboxamide formyl-transferase/IMP cyclohydrolase |
M |
Rv0957 |
– |
88.1% |
ML0183 |
moeA1 |
putative molybdopterin biosynthesis protein |
CW |
Rv0994 |
Pd |
88.3% |
ML0210cc |
ppa |
putative inorganic pyrophosphatase |
M |
Rv3628 |
Pd |
89.5% |
ML0235 |
clpC |
putative ATP-dependent Clp protease ATP-binding subunit ClpC |
M/CW |
Rv3596c |
Pd |
97.2% |
ML0255 |
eno |
putative enolase |
M |
Rv1023 |
P |
88.8% |
ML0269c |
fgd1 |
putative F-420-dependent glucose-6-phosphate dehydrogenase |
C |
Rv0407 |
P |
89.3% |
ML0297cc |
thiG |
putative thiamine biosynthesis protein |
CW |
Rv0417 |
– |
86.8% |
ML0348 |
|
possible coenzyme F420-dependent oxidoreductase |
C/M |
Rv3520c |
– |
86.8% |
ML0365 |
rpsI |
30S ribosomal protein S9 |
M |
Rv3442c |
– |
83.2% |
ML0379 |
gcp |
probable O-sialoglycoprotein endopeptidase |
C |
Rv3419c |
– |
86.1% |
ML0388 |
guaB3 |
putative inosine-5’-monophosphate dehydrogenase |
C/M |
Rv3410c |
– |
90.5% |
ML0393c |
|
probable hydrolase |
C |
Rv3400 |
P |
74.4% |
ML0418 |
|
putative oxidoreductase |
CW |
Rv3368c |
– |
81.9% |
ML0429c |
|
probable short-chain type dehydrogenase/reductase |
C |
Rv2509 |
Pd |
88.8% |
ML0485c |
gabT |
putative 4-aminobutyrate aminotransferase |
CW |
Rv2589 |
– |
83.7% |
ML0521 |
pepQ |
putative cytoplasmic peptidase PepQ |
C |
Rv2535c |
– |
83.0% |
ML0537 |
pyrF |
orotidine 5’-phosphate decarboxylase |
CW |
Rv1385 |
– |
77.3% |
ML0544 |
metK |
putative S-adenosylmethionine synthase |
C/M |
Rv1392 |
P/Td |
91.3% |
ML0551 |
|
putative methyltransferase |
C |
Rv1405c |
– |
77.7% |
ML0559 |
ribA |
putative GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase |
M |
Rv1415 |
P |
93.4% |
ML0570 |
gap |
glyceraldehyde 3-phosphate dehydrogenase |
M |
Rv1436 |
Pd |
89.1% |
ML0572 |
tpi |
triosephosphate isomerase |
C |
Rv1438 |
Pd |
83.9% |
ML0674c |
folD |
putative methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase |
C |
Rv3356c |
P |
86.5% |
ML0685c |
|
putative hydrolase |
M |
Rv3337 Rv3338 |
– – |
74.6% |
ML0763 |
pmmA |
putative phosphomannomutase |
CW |
Rv3257c |
– |
83.1% |
ML0839c |
cysK |
putative cysteine synthase |
C/M |
Rv2334 |
P |
85.8% |
ML0861c |
sucB |
putative dihydrolipoamide acyltransferase |
C |
Rv2215 |
Pd |
81.8% |
ML0873 |
adk |
putative adenosine kinase |
C |
Rv2202c |
– |
83.3% |
ML0925 |
glnA |
glutamine synthase class I |
M |
Rv2220 |
Pd |
91.8% |
ML0961c |
metE |
5-methyltetrahydropteroyltriglutamate-homocystein methyltransferase |
C/CW |
Rv1133c |
Pd |
85.0% |
ML0985 |
|
possible glycosyltransferase |
CW |
Rv2739c |
– |
80.9% |
ML0995 |
miaA |
tRNA [delta](2)-isopentenyl-pyrophosphate transferase |
CW |
Rv2727c |
– |
82.2% |
ML1059 |
dapE |
succinyl-diaminopimelate desuccinylase |
M |
Rv1202 |
– |
86.7% |
ML1091 |
mdh |
probable malate dehydrogenase |
C |
Rv1240 |
Pd |
89.1% |
ML1095c |
odhA/ sucA |
2-oxoglutarate dehydrogenase, E1 components |
M |
Rv1248c |
Pd |
89.0% |
ML1129 |
hom |
homoserine dehydrogenase |
M |
Rv1294 |
– |
99.8% |
ML1142 |
atpH |
bi-domained ATP synthase B, [delta] chain protein |
M |
Rv1307 |
P/Td |
77.8% |
ML1143 |
atpA |
ATP synthase [alpha] chain |
C |
Rv1308 |
P/Td |
69.0% |
ML1144 |
atpG |
ATP synthase [gamma] chain |
M/CW |
Rv1309 |
P/Td |
83.9% |
ML1145 |
atpD |
ATP synthase [beta] chain |
C/M |
Rv1310 |
P/Td |
92.6% |
ML1167 |
|
possible hydrolase |
M |
Rv1333 |
– |
76.7% |
ML1257 |
hisD |
histidinol dehydrogenase |
CW |
Rv1599 |
– |
84.8% |
ML1307c |
metH |
probable 5-methyltetrahydrofolate-homocystein methyltransferase metH (methionine synthase, vitamin-B12 dependent isozyme) |
C |
Rv2124c |
Pd |
88.3% |
ML1340c |
ribD |
possible bifunctional enzyme riboflavin biosynthesis protein RibD + 5-amino-6-uracil reductase |
C |
Rv2671 |
Pd |
72.9% |
ML1469c |
ndk |
nucleoside diphosphate kinase NDK |
C |
Rv2445c |
P |
87.4% |
ML1480 |
clpP |
ATP-dependent Clp protease proteolytic subunit |
C |
Rv2461c |
– |
95.0% |
ML1513c |
dapA |
probable dihydrodipicolinate synthase DAPA (DHDPS) |
C |
Rv2753c |
– |
86.7% |
ML1669 |
|
probable oxidoreductase |
C |
Rv2971 |
P |
79.8% |
ML1685c |
leuC |
3-isopropylmalate dehydratase large subunit |
CW |
Rv2988c |
P/Td |
88.7% |
ML1691c |
leuB |
3-isopropylmalate dehydrogenase |
M |
Rv2995c |
T |
83.9% |
ML1694c |
ilvC |
ketol-acid reductoisomerase IlvC |
C |
Rv3001c |
P/Td |
86.2% |
ML1696c |
ilvB |
probable acetolactate syntase (large subunit) IlvB |
C |
Rv3003c |
P |
87.1% |
ML1712c |
fixA |
probable electron transfer flavoprotein (beta subunit) FixA |
C |
Rv3029c |
Pd |
95.1% |
ML1730 |
adhA |
alcohol dehydrogenase |
CW |
Rv3045 |
Pd |
85.8% |
ML1832c |
kad |
probable adenylate kinase Kad |
C |
Rv0733 |
P |
83.4% |
ML1942 |
|
probable cholesterol dehydrogenase |
CW |
Rv1106c |
P |
75.5% |
ML1950cc |
|
carbohydrate degrading enzyme |
M |
Rv1096 |
– |
81.3% |
ML1985cc |
aceA |
isocitrate lyase |
M/CW |
Rv1916 |
T |
87.9% |
ML2011 |
aao |
probable D-amino acido oxidase AAO |
C |
Rv1905c |
– |
71.4% |
ML2046 |
lldD2 |
L-lactate dehydrogenase |
M |
Rv1872c |
P/Td |
85.0% |
ML2088c |
|
putative cytochrome P450 |
C/M |
Rv1880c |
– |
38.0% |
ML2130c |
gltA2 |
citrate synthase GLTA2 |
C/M |
Rv0896 |
P |
91.0% |
ML2226c |
ptrB |
protease II |
CW |
Rv0781 Rv0782 |
– |
69.9% 77.8% |
ML2227c |
purC |
phosphoribosylaminoimidazole-succinocarboxamide synthase |
M |
Rv0780 |
– |
81.5% |
ML2322c |
asd |
aspartate semialdehyde dehydrogenase |
M |
Rv3708c |
– |
84.4% |
ML2324 |
leuA |
probable 4-dihydroxy-2-naphthoate octaprenyltransferase 2-isopropylmalate synthase |
CW |
Rv3710 |
P |
80.6% |
ML2387c |
lpd |
dihydrolipoamide dehydrogenase Lpd |
M |
Rv0462 |
P |
83.1% |
ML2394c |
metB |
cystathionine [gamma]-synthase |
M |
Rv1079 |
P |
87.3% |
ML2396c |
cysM2 |
probable cystathionine [beta]-synthase CBS |
C |
Rv1077 |
P |
90.1% |
ML2406c |
menA |
UDP-galactose 4-epimerase |
CW |
Rv0534c |
– |
80.6% |
ML2419c |
hemB |
hemB, [delta]-aminolevulinic acid dehydratase |
CW |
Rv0512 |
– |
87.5% |
ML2428c |
galE2 |
probable UDP-galactose 4-epimerase GALE2 |
C |
Rv0501 |
P |
84.0% |
ML2430c |
proC |
pyrroline-5-carboxylate reductase |
M/CW |
Rv0500 |
– |
82.4% |
ML2441cc |
gpm |
phosphoglycerate mutase |
C |
Rv0489 |
– |
89.0% |
ML2449c |
|
putative amidohydrolase |
CW |
Rv0480c |
P |
81.9% |
ML2474 |
|
possible cytidine/deoxycytidylate deaminase |
CW |
Rv3752c |
– |
87.4% |
ML2501c |
|
probable iron-sulphur-binding reductase |
CW |
Rv0338c |
P |
78.1% |
ML2573 |
gabD |
probable succinate-semialdehyde dehydrogenase [NADP+] dependent |
C |
Rv0234c |
P |
82.9% |
ML2659cc |
pepA |
probable secreted serine protease |
M |
Rv0125 |
T |
70.1% |
ML2672c |
icd2 |
probable isocitrate dehydrogenase [NADP+] |
M |
Rv0066c |
P |
85.4% |
Class VIII – Hypothetical Unknown |
||||||
ML0959 |
|
hypothetical protein |
CW |
– |
– |
– |
Class IX – Regulatory Proteins |
||||||
ML0639c |
whiB7 |
putative transcriptional regulator |
CW |
Rv3197A |
P |
69.3% |
ML1286 |
|
possible two-component response regulatory protein |
CW |
Rv1626 |
P |
90.7% |
ML1511 |
npdA |
probable NAD-dependent deacetylase NpdA |
M |
Rv1151c |
– |
85.2% |
ML2302 |
|
putative Crp/Fnr-family transcriptional regulator |
C/M/CW |
Rv3676 |
P |
96.0% |
ML2440c |
senX3 |
probable two-component system sensor histidine kinase |
M |
Rv0490 |
P |
84.0% |
Class X – Conserved Hypotheticals |
||||||
ML0129c |
|
conserved hypothetical protein |
M |
Rv2953 |
P/T |
86.6% |
ML0333c |
|
conserved hypothetical protein |
C |
– |
– |
– |
ML0369c |
|
conserved hypothetical protein |
CW |
– |
– |
– |
ML0405 |
|
conserved hypothetical protein |
M |
Rv3616c |
T |
62.7% |
ML0447 |
|
conserved hypothetical protein |
M/CW |
– |
– |
– |
ML0593 |
|
conserved hypothetical protein |
M |
Rv1461 |
P |
54.3% |
ML0703 |
|
conserved hypothetical protein |
M |
Rv3311 |
– |
77.5% |
ML0781 |
|
conserved hypothetical protein |
C |
Rv3237c |
T |
80.6% |
ML0901 |
|
conserved hypothetical protein |
CW |
Rv2172c |
T |
80.9% |
ML1040 |
|
conserved hypothetical protein |
M |
Rv2681 |
P |
77.4% |
ML1330 |
|
conserved hypothetical protein |
CW |
Rv2095c |
– |
74.2% |
ML1368 |
|
conserved hypothetical protein |
CW |
Rv1709 |
– |
78.9% |
ML1369 |
|
conserved hypothetical protein |
M/CW |
Rv1710 |
– |
77.9% |
ML1380 |
|
conserved hypothetical protein |
M/CW |
Rv1780 |
P |
82.4% |
ML1418c |
|
conserved hypothetical protein |
C/CW |
Rv1732c |
P |
86.3% |
ML1423c |
|
conserved hypothetical protein |
M |
Rv2037 |
P/T |
80.5% |
ML1444 |
|
conserved hypothetical protein |
M |
Rv2054 |
P |
76.1% |
ML1637c |
|
conserved hypothetical protein |
CW |
Rv2228c |
– |
76.8% |
ML1661c |
|
conserved hypothetical protein |
CW |
Rv2927c |
– |
90.2% |
ML1704 |
|
conserved hypothetical protein |
CW |
Rv3013 |
– |
84.3% |
ML1706c |
|
conserved hypothetical protein |
C |
Rv3015c |
– |
78.3% |
ML1782c |
|
conserved hypothetical protein |
CW |
Rv2257c |
– |
76.4% |
ML2031 |
|
conserved hypothetical protein |
CW |
Rv1883c |
– |
76.2% |
ML2070 |
|
conserved hypothetical protein |
M |
Rv1836c |
P |
66.0% |
ML2113c |
|
conserved hypothetical protein |
CW |
Rv0910c |
– |
83.9% |
ML2336 |
|
conserved hypothetical protein |
CW |
Rv3722c |
T |
87.6% |
ML2465 |
|
conserved hypothetical protein |
M |
Rv0464c |
P/T |
67.4% |
ML2491 |
|
conserved hypothetical protein |
M/CW |
Rv1754c |
P |
61.5% |
ML2627 |
|
conserved hypothetical protein |
CW |
Rv0216 |
P |
35.8% |
ML2640c |
|
conserved hypothetical protein |
CW |
Rv0146 |
P |
78.1% |
a Functional classification and ID refer to the original annotated M. leprae gene number assigned by Sanger ID from Cole ST et al. 2001. Nature 409:1007–1011.
c Proteins also shown to be expressed by transcriptional analysis.
d Proteins identified by subcellular protein profiling from Mawuenyega KG et al. 2005. Mol Biol Cell 16:396–404.
C – cytosolic/soluble; M – membrane; CW – cell wall; T – gene expression demonstrated by transcriptional analysis; P – gene expression demonstrated by proteomic analysis.